An In Vitro System for Evaluating Molecular Targeted Drugs Using Lung Patient-Derived Tumor Organoids

An In Vitro System for Evaluating Molecular Targeted Drugs Using Lung Patient-Derived Tumor Organoids

Patient-derived tumor organoids (PDOs) represent a promising preclinical cancer model that better replicates disease, compared with traditional cell culture models. We have established PDOs from various human tumors to accurately and efficiently recapitulate the tissue architecture and function. Mol...

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Bibliographic Details
Main Authors: Nobuhiko Takahashi, Hirotaka Hoshi, Arisa Higa, Gen Hiyama, Hirosumi Tamura, Mayu Ogawa, Kosuke Takagi, Kazuhito Goda, Naoyuki Okabe, Satoshi Muto, Hiroyuki Suzuki, Kenju Shimomura, Shinya Watanabe, Motoki Takagi
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
molecular targeted therapy
cancer immunotherapy
cancer immunity
molecular targeted drugs
antibody drug
antibody-drug conjugate
immune checkpoint inhibitor
patient-derived tumor organoid
antibody-dependent cellular cytotoxicity
3D cell-analysis system
Online Access:https://www.mdpi.com/2073-4409/8/5/481

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https://www.mdpi.com/2073-4409/8/5/481

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