The Notch ligand DNER regulates macrophage IFNγ release in chronic obstructive pulmonary diseaseResearch in context

Background: Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death worldwide with no curative therapy. A non-canonical Notch ligand, DNER, has been recently identified in GWAS to associate with COPD severity, but its function and contribution to COPD is unknown. Methods: DN...

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Bibliographic Details
Main Authors: Carolina Ballester-López, Thomas M. Conlon, Zeynep Ertüz, Flavia R. Greiffo, Martin Irmler, Stijn E. Verleden, Johannes Beckers, Isis E. Fernandez, Oliver Eickelberg, Ali Önder Yildirim
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419301999