Analysis of HBV Genomes Integrated into the Genomes of Human Hepatoma PLC/PRF/5 Cells by HBV Sequence Capture-Based Next-Generation Sequencing

Analysis of HBV Genomes Integrated into the Genomes of Human Hepatoma PLC/PRF/5 Cells by HBV Sequence Capture-Based Next-Generation Sequencing

Hepatitis B virus (HBV) infection is a leading cause of hepatocellular carcinoma (HCC) worldwide. The integration of HBV genomic DNA into the host genome occurs randomly, early after infection, and is associated with hepatocarcinogenesis in HBV-infected patients. Therefore, it is important to analyz...

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Bibliographic Details
Main Authors: Tomotaka Ishii, Akinori Tamura, Toshikatsu Shibata, Kazumichi Kuroda, Tatsuo Kanda, Masaya Sugiyama, Masashi Mizokami, Mitsuhiko Moriyama
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Genes
Subjects:
chromosome
HBV
HCC
hepatocarcinogenesis
Huh7
integration
Online Access:https://www.mdpi.com/2073-4425/11/6/661

Internet

https://www.mdpi.com/2073-4425/11/6/661

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