Catechol-O-methyltransferase Val158Met polymorphism on the relationship between white matter hyperintensity and cognition in healthy people.

BACKGROUND: White matter lesions can be easily observed on T2-weighted MR images, and are termed white matter hyperintensities (WMH). Their presence may be correlated with cognitive impairment; however, the relationship between regional WMH volume and catechol-O-methyltransferase (COMT) Val158Met po...

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Main Authors: Mu-En Liu, Chu-Chung Huang, Albert C Yang, Pei-Chi Tu, Heng-Liang Yeh, Chen-Jee Hong, Ying-Jay Liou, Jin-Fan Chen, Kun-Hsien Chou, Ching-Po Lin, Shih-Jen Tsai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3923794?pdf=render