Effect of methionine load on homocysteine levels, lipid peroxidation and DNA damage in rats receiving ethanol

Changes in the metabolism of methionine can cause hyperhomocysteinemia, inducing a triad of atherosclerosis, hypertension, and increased oxidative stress. The generation of free radicals and oxidative damage to DNA is important in the liver damage caused by ethanol. In this study, the effect of meth...

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Bibliographic Details
Main Authors: Alceu Afonso Jordao Júnior, Fernanda Aparecida Domenici, Renata Cristina Lataro, Guilherme Vannucchi Portari, Helio Vannucchi
Format: Article
Language:English
Published: Universidade de São Paulo 2009-12-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000400014