Hemin binding and oxidation of lipoproteins in serum: mechanisms and effect on the interaction of LDL with human macrophages1

Hemin binding and oxidation of lipoproteins in serum: mechanisms and effect on the interaction of LDL with human macrophages1

Most models of lipoprotein oxidation by free radicals have excluded macromolecular plasma components from the system. This limits their biological significance because oxidation of lipoproteins appears to occur in the intima in the presence of a plasma ultrafiltrate. Hemin, a product of in vivo hemo...

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Bibliographic Details
Main Authors: Germán Camejo, Carina Halberg, Angela Manschik-Lundin, Eva Hurt-Camejo, Birgitta Rosengren, Helena Olsson, Göran I. Hansson, Gun-Britt Forsberg, Britt Ylhen
Format: Article
Language:English
Published: Elsevier 1998-04-01
Series:Journal of Lipid Research
Subjects:
lipoprotein oxidation
hemin binding
serum components
conjugated dienes
macrophages
lipoprotein degradation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520325645

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http://www.sciencedirect.com/science/article/pii/S0022227520325645

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