Hepatocyte growth factor gene-modified adipose-derived mesenchymal stem cells ameliorate radiation induced liver damage in a rat model.

Liver damage caused by radiotherapy is associated with a high mortality rate, but no established treatment exists. Adipose-derived mesenchymal stem cells (ADSCs) are capable of migration to injured tissue sites, where they aid in the repair of the damage. Hepatocyte growth factor (HGF) is critical f...

Full description

Bibliographic Details
Main Authors: Jiamin Zhang, Shiyuan Zhou, Yi Zhou, Feier Feng, Qianming Wang, Xiaolu Zhu, Huisheng Ai, Xiaojun Huang, Xiaohui Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4264768?pdf=render