Loss of Adenylyl Cyclase 6 in Leptin Receptor‐Expressing Stromal Cells Attenuates Loading‐Induced Endosteal Bone Formation

Loss of Adenylyl Cyclase 6 in Leptin Receptor‐Expressing Stromal Cells Attenuates Loading‐Induced Endosteal Bone Formation

ABSTRACT Bone marrow stromal/stem cells represent a quiescent cell population that replenish the osteoblast bone‐forming cell pool with age and in response to injury, maintaining bone mass and repair. A potent mediator of stromal/stem cell differentiation in vitro and bone formation in vivo is physi...

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Bibliographic Details
Main Authors: Mathieu Riffault, Gillian P Johnson, Madeline M Owen, Behzad Javaheri, Andrew A Pitsillides, David A Hoey
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:JBMR Plus
Subjects:
ADENYLYL CYCLASE 6
BONE ADAPTATION
IN VIVO MECHANICAL LOADING
MECHANOBIOLOGY
STEM CELLS
Online Access:https://doi.org/10.1002/jbm4.10408

Internet

https://doi.org/10.1002/jbm4.10408

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