Benchmarking HLA genotyping and clarifying HLA impact on survival in tumor immunotherapy

Benchmarking HLA genotyping and clarifying HLA impact on survival in tumor immunotherapy

Human leukocyte antigen (HLA) genotyping gains intensive attention due to its critical role in cancer immunotherapy. It is still a challenging issue to generate reliable HLA genotyping results through in silico tools. In addition, the survival impact of HLA alleles in tumor prognosis and immunothera...

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Bibliographic Details
Main Authors: Xiangyong Li, Chi Zhou, Ke Chen, Bingding Huang, Qi Liu, Hao Ye
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Molecular Oncology
Subjects:
HLA genotyping
immune cytolytic activity
tumor immunotherapy
tumor mutation burden
Online Access:https://doi.org/10.1002/1878-0261.12895

Internet

https://doi.org/10.1002/1878-0261.12895

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