A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies

A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies

The permeability barrier of nuclear pore complexes (NPCs) controls bulk nucleocytoplasmic exchange. It consists of nucleoporin domains rich in phenylalanine-glycine motifs (FG domains). As a bottom-up nanoscale model for the permeability barrier, we have used planar films produced with three differe...

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Bibliographic Details
Main Authors: Raphael Zahn, Dino Osmanović, Severin Ehret, Carolina Araya Callis, Steffen Frey, Murray Stewart, Changjiang You, Dirk Görlich, Bart W Hoogenboom, Ralf P Richter
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-04-01
Series:eLife
Subjects:
nucleo-cytoplasmic transport
nuclear transport receptor
intrinsically disordered proteins
quartz crystal microbalance
spectroscopic ellipsometry
computational modeling
Online Access:https://elifesciences.org/articles/14119

Internet

https://elifesciences.org/articles/14119

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