Taurine Administration Recovers Motor and Learning Deficits in an Angelman Syndrome Mouse Model

Taurine Administration Recovers Motor and Learning Deficits in an Angelman Syndrome Mouse Model

Angelman syndrome (AS, MIM 105830) is a rare neurodevelopmental disorder affecting 1:10–20,000 children. Patients show moderate to severe intellectual disability, ataxia and absence of speech. Studies on both post-mortem AS human brains and mouse models revealed dysfunctions in the extra synaptic ga...

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Bibliographic Details
Main Authors: Sara Guzzetti, Luciano Calzari, Lucia Buccarello, Valentina Cesari, Ivan Toschi, Stefania Cattaldo, Alessandro Mauro, Francesca Pregnolato, Silvia Michela Mazzola, Silvia Russo
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:International Journal of Molecular Sciences
Subjects:
Angelman syndrome
taurine oral administration
motor and learning recover of deficit
Online Access:http://www.mdpi.com/1422-0067/19/4/1088

Internet

http://www.mdpi.com/1422-0067/19/4/1088

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