In situ DESI-MSI lipidomic profiles of mucosal margin of oral squamous cell carcinoma

In situ DESI-MSI lipidomic profiles of mucosal margin of oral squamous cell carcinoma

Background: Although there is consensus that the optimal safe margin is ≥ 5mm, obtaining clear margins (≥5 mm) intraoperatively seems to be the major challenge. We applied a molecular diagnostic method at the lipidomic level to determine the safe surgical resection margin of OSCC by desorption elect...

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Bibliographic Details
Main Authors: Xihu Yang, Dr., Xiaowei Song, Xiaoxin Zhang, Vishnu Shankar, Shuai Wang, Yan Yang, Sheng Chen, Lei Zhang, Yanhong Ni, Dr., Richard N. Zare, Dr., Qingang Hu, Dr.
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:EBioMedicine
Subjects:
OSCC
DESI-MSI
Lipidomics
Surgical margin
Surgical resection distance
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421003224

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http://www.sciencedirect.com/science/article/pii/S2352396421003224

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