Identification of a novel peptide derived from the M-phase phosphoprotein 11 (MPP11) leukemic antigen recognized by human CD8+ cytotoxic T lymphocytes

BACKGROUND AND OBJECTIVES: There is an urgent need for the development of leukemia-targeted im-munotherapeutic approaches using defined leukemia-associated antigens that are preferentially expressed by most leukemia subtypes and absent or minimally expressed in vital tissues. M-phase phosphoprotein...

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Bibliographic Details
Main Authors: Ghofran Al Qudaihi, Cynthia Lehe, Anne Dickinson, Khaled Eltayeb, Walid Rasheed, Naeem Chaudhri, Mahmoud Aljurf, Said Dermime
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Hematology/Oncology and Stem Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1658387610500530