Versatile inhibitory effects of the flavonoid‐derived PI3K/Akt inhibitor, LY294002, on ATP‐binding cassette transporters that characterize stem cells

Abstract Stem cells are undifferentiated cells capable of proliferation, self‐renewal, and production of a large number of differentiated progeny. Stem cells exist even in malignancies. They are called cancer stem cells, which may represent the origin of these tumors and may be one of the reasons of...

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Bibliographic Details
Main Authors: Yasuo Imai, Hidetsugu Yamagishi, Yuko Ono, Yoshihiko Ueda
Format: Article
Language:English
Published: Wiley 2012-12-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/2001-1326-1-24