Impaired embryonic development in mice overexpressing the RNA-binding protein TIAR.

BACKGROUND: TIA-1-related (TIAR) protein is a shuttling RNA-binding protein involved in several steps of RNA metabolism. While in the nucleus TIAR participates to alternative splicing events, in the cytoplasm TIAR acts as a translational repressor on specific transcripts such as those containing AU-...

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Bibliographic Details
Main Authors: Yacine Kharraz, Pierre-Adrien Salmand, Anne Camus, Jacques Auriol, Cyril Gueydan, Véronique Kruys, Dominique Morello
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2893167?pdf=render