In vivo effects of antibodies from patients with anti-NMDA receptor encephalitis: further evidence of synaptic glutamatergic dysfunction

<p>Abstract</p> <p>Background</p> <p>A severe encephalitis that associates with auto-antibodies to the NR1 subunit of the NMDA receptor (NMDA-R) was recently reported. Patients' antibodies cause a decrease of the density of NMDA-R and synaptic mediated currents, bu...

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Bibliographic Details
Main Authors: Manto Mario, Dalmau Josep, Didelot Adrien, Rogemond Véronique, Honnorat Jérôme
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Orphanet Journal of Rare Diseases
Online Access:http://www.ojrd.com/content/5/1/31