Gelatin-Modified Calcium/Strontium Hydrogen Phosphates Stimulate Bone Regeneration in Osteoblast/Osteoclast Co-Culture and in Osteoporotic Rat Femur Defects—In Vitro to In Vivo Translation

Gelatin-Modified Calcium/Strontium Hydrogen Phosphates Stimulate Bone Regeneration in Osteoblast/Osteoclast Co-Culture and in Osteoporotic Rat Femur Defects—In Vitro to In Vivo Translation

The development and characterization of biomaterials for bone replacement in case of large defects in preconditioned bone (e.g., osteoporosis) require close cooperation of various disciplines. Of particular interest are effects observed in vitro at the cellular level and their in vivo representation...

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Bibliographic Details
Main Authors: Benjamin Kruppke, Seemun Ray, Volker Alt, Marcus Rohnke, Christine Kern, Marian Kampschulte, Christiane Heinemann, Matthäus Budak, Josephine Adam, Nils Döhner, Lucretia Franz-Forsthoffer, Thaqif El Khassawna, Christian Heiss, Thomas Hanke, Ulrich Thormann
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Molecules
Subjects:
biomimetic material
osteoporosis
fracture defect
co-culture
calcium phosphate
strontium phosphate
Online Access:https://www.mdpi.com/1420-3049/25/21/5103

Internet

https://www.mdpi.com/1420-3049/25/21/5103

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