Urinary TERT promoter mutations are detectable up to 10 years prior to clinical diagnosis of bladder cancer: Evidence from the Golestan Cohort Study

Urinary TERT promoter mutations are detectable up to 10 years prior to clinical diagnosis of bladder cancer: Evidence from the Golestan Cohort Study

Background: Detecting pre-clinical bladder cancer (BC) using urinary biomarkers may provide a valuable opportunity for screening and management. Telomerase reverse transcriptase (TERT) promoter mutations detectable in urine have emerged as promising BC biomarkers. Methods: We performed a nested case...

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Bibliographic Details
Main Authors: Md Ismail Hosen, Mahdi Sheikh, Maria Zvereva, Ghislaine Scelo, Nathalie Forey, Geoffroy Durand, Catherine Voegele, Hossein Poustchi, Masoud Khoshnia, Gholamreza Roshandel, Masoud Sotoudeh, Arash Nikmanesh, Arash Etemadi, Patrice Hodonou Avogbe, Priscilia Chopard, Tiffany Myriam Delhomme, Matthieu Foll, Arnaud Manel, Emmanuel Vian, Elisabete Weiderpass, Farin Kamangar, Paolo Boffetta, Paul D. Pharaoh, Sanford M. Dawsey, Christian C. Abnet, Paul Brennan, James McKay, Reza Malekzadeh, Florence Le Calvez-Kelm
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420300189

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http://www.sciencedirect.com/science/article/pii/S2352396420300189

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