Ubiquitin-specific peptidase 3 induces TPA-mediated leukemia cell differentiation via regulating H2AK119ub

Acute myeloid leukemia (AML) is the most common type of leukemia in adults. Owing to the chemotherapy associated side effects and toxicity, it is necessary to find a new mechanism, which can identify new potential therapeutic targets at the molecular level. Here, we identified new target genes that...

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Bibliographic Details
Main Authors: Yun-Cheol Chae, Hyeonsoo Jung, Ji-Young Kim, Dong Ho Lee, Sang-Beom Seo
Format: Article
Language:English
Published: Taylor & Francis Group 2019-09-01
Series:Animal Cells and Systems
Subjects:
tpa
aml
Online Access:http://dx.doi.org/10.1080/19768354.2019.1661283