SGLT2 inhibitor ipragliflozin alone and combined with pioglitazone prevents progression of nonalcoholic steatohepatitis in a type 2 diabetes rodent model

Abstract Nonalcoholic steatohepatitis (NASH) has become the most common cause of chronic liver disease worldwide in recent years. The pathogenesis of NASH is closely linked to metabolic diseases such as insulin resistance, obesity, dyslipidemia, and type 2 diabetes. However, there is currently no ph...

Full description

Bibliographic Details
Main Authors: Atsuo Tahara, Toshiyuki Takasu
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14286