Increased CD45RA+ FoxP3(low) regulatory T cells with impaired suppressive function in patients with systemic lupus erythematosus.

Increased CD45RA+ FoxP3(low) regulatory T cells with impaired suppressive function in patients with systemic lupus erythematosus.

BACKGROUND: The role of naturally occurring regulatory T cells (Treg) in the control of the development of systemic lupus erythematosus (SLE) has not been well defined. Therefore, we dissect the phenotypically heterogeneous CD4(+)FoxP3(+) T cells into subpopulations during the dynamic SLE developmen...

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Bibliographic Details
Main Authors: Xiujun Pan, Xiangliang Yuan, Yingxia Zheng, Weiwei Wang, Jianping Shan, Fujun Lin, Gengru Jiang, Yuan H Yang, Die Wang, Dakang Xu, Lisong Shen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3323568?pdf=render

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http://europepmc.org/articles/PMC3323568?pdf=render

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