Establishment of a new murine elastase-induced aneurysm model combined with transplantation.

The aim of our study was to develop a reproducible murine model of elastase-induced aneurysm formation combined with aortic transplantation.Adult male mice (n = 6-9 per group) underwent infrarenal, orthotopic transplantation of the aorta treated with elastase or left untreated. Subsequently, both gr...

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Bibliographic Details
Main Authors: Zuzanna Rowinska, Simone Gorressen, Marc W Merx, Thomas A Koeppel, Elisa A Liehn, Alma Zernecke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4113210?pdf=render