Identification of a novel IL-5 signaling pathway in chronic pancreatitis and crosstalk with pancreatic tumor cells

Identification of a novel IL-5 signaling pathway in chronic pancreatitis and crosstalk with pancreatic tumor cells

Abstract Background While inflammation is associated with pancreatic cancer, the underlying mechanisms leading to cancer initiation are still being delineated. Eosinophils may promote or inhibit tumor growth, although the specific role in pancreatic cancer has yet to be determined. Eosinophil-suppor...

Full description

Bibliographic Details
Main Authors: Sarah B. Gitto, Jordan M. Beardsley, Sai Preethi Nakkina, Jeremiah L. Oyer, Kathryn A. Cline, Sally A. Litherland, Alicja J. Copik, Amr S. Khaled, Na’im Fanaian, J. Pablo Arnoletti, Deborah A. Altomare
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Cell Communication and Signaling
Subjects:
Pancreatic ductal adenocarcinoma
Pancreatitis
IL-5
IL-5R
Eosinophils
Online Access:http://link.springer.com/article/10.1186/s12964-020-00594-x

Internet

http://link.springer.com/article/10.1186/s12964-020-00594-x

Similar Items