COX-independent mechanisms of cancer chemoprevention by anti-inflammatory drugs

Epidemiological and clinical studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs), including cyclooxygenase (COX)-2 selective inhibitors, reduce the risk of developing cancer. Experimental studies in human cancer cell lines and rodent models of carcinogenesis support these observation...

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Bibliographic Details
Main Authors: Evrim eGurpinar, William E Grizzle, Gary A Piazza
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00181/full