Effect of mesenchymal precursor cells on the systemic inflammatory response and endothelial dysfunction in an ovine model of collagen-induced arthritis.

Mesenchymal precursor cells (MPC) are reported to possess immunomodulatory properties that may prove beneficial in autoimmune and other inflammatory conditions. However, their mechanism of action is poorly understood. A collagen-induced arthritis model has been previously developed which demonstrate...

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Bibliographic Details
Main Authors: Laura M Dooley, Anwar Abdalmula, Elizabeth A Washington, Claire Kaufman, Elizabeth M Tudor, Peter Ghosh, Silviu Itescu, Wayne G Kimpton, Simon R Bailey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4423911?pdf=render