Developmental lineage priming in Dictyostelium by heterogeneous Ras activation

In cell culture, genetically identical cells often exhibit heterogeneous behavior, with only ‘lineage primed’ cells responding to differentiation inducing signals. It has recently been proposed that such heterogeneity exists during normal embryonic development to allow position independent patternin...

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Bibliographic Details
Main Authors: Alex Chattwood, Koki Nagayama, Parvin Bolourani, Lauren Harkin, Marzieh Kamjoo, Gerald Weeks, Christopher RL Thompson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-11-01
Series:eLife
Subjects:
Ras
Online Access:https://elifesciences.org/articles/01067