Developmental lineage priming in Dictyostelium by heterogeneous Ras activation
In cell culture, genetically identical cells often exhibit heterogeneous behavior, with only ‘lineage primed’ cells responding to differentiation inducing signals. It has recently been proposed that such heterogeneity exists during normal embryonic development to allow position independent patternin...
Main Authors: | Alex Chattwood, Koki Nagayama, Parvin Bolourani, Lauren Harkin, Marzieh Kamjoo, Gerald Weeks, Christopher RL Thompson |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2013-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/01067 |
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