Ubiquitination of Nonhistone Proteins in Cancer Development and Treatment

Ubiquitination of Nonhistone Proteins in Cancer Development and Treatment

Ubiquitination, a crucial post-translation modification, regulates the localization and stability of the substrate proteins including nonhistone proteins. The ubiquitin-proteasome system (UPS) on nonhistone proteins plays a critical role in many cellular processes such as DNA repair, transcription,...

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Bibliographic Details
Main Authors: Xiuzhen Zhang, Tong Meng, Shuaishuai Cui, Ling Feng, Dongwu Liu, Qiuxiang Pang, Ping Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
ubiquitination
E3 ligase
deubiquitinase
nonhistone protein
cancer
proteolysis-targeting chimeras
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.621294/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.621294/full

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