XPA, XPC, and XPD Modulate Sensitivity in Gastric Cisplatin Resistance Cancer Cells

XPA, XPC, and XPD Modulate Sensitivity in Gastric Cisplatin Resistance Cancer Cells

Cisplatin is an election drug widely used in clinic for the treatment of advanced gastric cancer. However, the heterogeneity of the gastric tumors and its resistance to the drugs, make in some cases the response very low and the prognosis unpredictable. In this manuscript we aim to find the molecula...

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Bibliographic Details
Main Authors: Natalia Pajuelo-Lozano, Jone Bargiela-Iparraguirre, Gemma Dominguez, Adoracion G. Quiroga, Rosario Perona, Isabel Sanchez-Perez
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pharmacology
Subjects:
gastric cancer
apoptosis
cisplatin
NER repair
Bcl-2 family
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01197/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01197/full

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