Parameter, noise, and tree topology effects in tumor phylogeny inference
Abstract Background Accurate inference of the evolutionary history of a tumor has important implications for understanding and potentially treating the disease. While a number of methods have been proposed to reconstruct the evolutionary history of a tumor from DNA sequencing data, it is not clear h...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | BMC Medical Genomics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12920-019-0626-0 |