Parameter, noise, and tree topology effects in tumor phylogeny inference

Abstract Background Accurate inference of the evolutionary history of a tumor has important implications for understanding and potentially treating the disease. While a number of methods have been proposed to reconstruct the evolutionary history of a tumor from DNA sequencing data, it is not clear h...

Full description

Bibliographic Details
Main Authors: Kiran Tomlinson, Layla Oesper
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Medical Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12920-019-0626-0