Oral administration of the K<sub>ATP </sub>channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis

Oral administration of the K<sub>ATP </sub>channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis

<p>Abstract</p> <p>Background</p> <p>Multiple Sclerosis (MS) is an acquired inflammatory demyelinating disorder of the central nervous system (CNS) and is the leading cause of nontraumatic disability among young adults. Activated microglial cells are important effectors...

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Bibliographic Details
Main Authors: Mahy Nicole, Rodríguez Manuel J, Gimeno-Bayon Javier, Pastén-Zamorano Andrea, Mancera Pilar, Espinosa-Parrilla Juan F, Virgili Noemí, Pugliese Marco
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Journal of Neuroinflammation
Subjects:
Diazoxide
experimental autoimmune encephalomyelitis
K<sub>ATP </sub>channel
microglia
multiple sclerosis
neuroprotection
Online Access:http://www.jneuroinflammation.com/content/8/1/149

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http://www.jneuroinflammation.com/content/8/1/149

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