GUANIDINOACETIC ACID(GAA) IN PATIENTS WITH CHRONIC KIDNEY DISEASE(CKD) AND DIABETES MELLITUS(DM)

GAA is the precursor of creatine, an essential in the energy metabolism of muscle and nerve tissue. GAA is mainly produced in the kidney. GAA production was reported to be suppressed in the streptozotocin-induced DM rats. However, GAA metabolism has not been really investigated in CKD or DM patients...

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Bibliographic Details
Main Authors: Yoshiharu Tsubakihara, Terumasa Hayashi, Tatsuya Shoji
Format: Article
Language:English
Published: The Korean Society of Nephrology 2012-06-01
Series:Kidney Research and Clinical Practice
Online Access:http://www.sciencedirect.com/science/article/pii/S2211913212006146