Lower-Molecular-Weight Chitosan-Treated Polyethyleneimine: a Practical Strategy For Gene Delivery to Mesenchymal Stem Cells

Lower-Molecular-Weight Chitosan-Treated Polyethyleneimine: a Practical Strategy For Gene Delivery to Mesenchymal Stem Cells

Background/Aims: Genetic modification of mesenchymal stem cells (MSCs) is an essential requirement for their use as a delivery vehicle. To achieve higher transfection efficiency and better reproducibility than previously synthesized chitosan (100 kDa)-polyethylenimine (PEI; 1200 Da), we synthesized...

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Bibliographic Details
Main Authors: Minchen Liu, Lu Zhang, Qingqing Zhao, Xinchi Jiang, Luyao Wu, Yulan Hu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Mesenchymal stem cells
Gene delivery
Safety evaluation
Chitosan
Polyethylenimine
Online Access:https://www.karger.com/Article/FullText/494585

Internet

https://www.karger.com/Article/FullText/494585

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