Alcelaphine herpesvirus 1 genes A7 and A8 regulate viral spread and are essential for malignant catarrhal fever.

Alcelaphine herpesvirus 1 (AlHV-1) is a gammaherpesvirus that is carried asymptomatically by wildebeest. Upon cross-species transmission to other ruminants, including domestic cattle, AlHV-1 induces malignant catarrhal fever (MCF), which is a fatal lymphoproliferative disease resulting from prolifer...

Full description

Bibliographic Details
Main Authors: Françoise Myster, Mei-Jiao Gong, Justine Javaux, Nicolás M Suárez, Gavin S Wilkie, Tim Connelley, Alain Vanderplasschen, Andrew J Davison, Benjamin G Dewals
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008405