Multi-task learning sparse group lasso: a method for quantifying antigenicity of influenza A(H1N1) virus using mutations and variations in glycosylation of Hemagglutinin

Multi-task learning sparse group lasso: a method for quantifying antigenicity of influenza A(H1N1) virus using mutations and variations in glycosylation of Hemagglutinin

Abstract Background In addition to causing the pandemic influenza outbreaks of 1918 and 2009, subtype H1N1 influenza A viruses (IAVs) have caused seasonal epidemics since 1977. Antigenic property of influenza viruses are determined by both protein sequence and N-linked glycosylation of influenza gly...

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Bibliographic Details
Main Authors: Lei Li, Deborah Chang, Lei Han, Xiaojian Zhang, Joseph Zaia, Xiu-Feng Wan
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Bioinformatics
Subjects:
Influenza virus
H1N1
Multi-task learning
Sparse learning
Group lasso
LASSO
Online Access:http://link.springer.com/article/10.1186/s12859-020-3527-5

Internet

http://link.springer.com/article/10.1186/s12859-020-3527-5

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