Disulfiram Alone Functions as a Radiosensitizer for Pancreatic Cancer Both In Vitro and In Vivo

Disulfiram Alone Functions as a Radiosensitizer for Pancreatic Cancer Both In Vitro and In Vivo

The prognosis of pancreatic cancer remains very poor worldwide, partly due to the lack of specificity of early symptoms and innate resistance to chemo-/radiotherapy. Disulfiram (DSF), an anti-alcoholism drug widely used in the clinic, has been known for decades for its antitumor effects when simulta...

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Bibliographic Details
Main Authors: Ying Xu, Lunjie Lu, Judong Luo, Lili Wang, Qi Zhang, Jianping Cao, Yang Jiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
disulfiram
pancreatic cancer
radiosensitivity
DNA damage
RNA sequencing
cell adhesion molecule signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.683695/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.683695/full

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