Yeast Gup1(2) Proteins Are Homologues of the Hedgehog Morphogens Acyltransferases HHAT(L): Facts and Implications

In multiple tissues, the Hedgehog secreted morphogen activates in the receiving cells a pathway involved in cell fate, proliferation and differentiation in the receiving cells. This pathway is particularly important during embryogenesis. The protein HHAT (Hedgehog O-acyltransferase) modifies Hh morp...

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Bibliographic Details
Main Authors: Cândida Lucas, Célia Ferreira, Giulia Cazzanelli, Ricardo Franco-Duarte, Joana Tulha
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Journal of Developmental Biology
Subjects:
GUP
Online Access:http://www.mdpi.com/2221-3759/4/4/33