IGF Binding Protein-5 Induces Cell Senescence

IGF Binding Protein-5 Induces Cell Senescence

Cellular senescence is the complex process of deterioration that drives the aging of an organism, resulting in the progressive loss of organ function and eventually phenotypic aging. Senescent cells undergo irreversible growth arrest, usually by inducing telomere shortening. Alternatively, senescenc...

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Bibliographic Details
Main Authors: Fumihiro Sanada, Yoshiaki Taniyama, Jun Muratsu, Rei Otsu, Hideo Shimizu, Hiromi Rakugi, Ryuichi Morishita
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Endocrinology
Subjects:
IGF binding protein-5
cell senescence
inflammation
coagulation system
age-related disease
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2018.00053/full

Internet

http://journal.frontiersin.org/article/10.3389/fendo.2018.00053/full

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