A DJ-1 Based Peptide Attenuates Dopaminergic Degeneration in Mice Models of Parkinson's Disease via Enhancing Nrf2.

A DJ-1 Based Peptide Attenuates Dopaminergic Degeneration in Mice Models of Parkinson's Disease via Enhancing Nrf2.

Drugs currently used for treating Parkinson's disease patients provide symptomatic relief without altering the neurodegenerative process. Our aim was to examine the possibility of using DJ-1 (PARK7), as a novel therapeutic target for Parkinson's disease. We designed a short peptide, named...

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Bibliographic Details
Main Authors: Nirit Lev, Yael Barhum, Tali Ben-Zur, Israel Aharony, Lena Trifonov, Noa Regev, Eldad Melamed, Arie Gruzman, Daniel Offen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4449207?pdf=render

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http://europepmc.org/articles/PMC4449207?pdf=render

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