The Cytoskeletal Protein Cyclase-Associated Protein 1 (CAP1) in Breast Cancer: Context-Dependent Roles in Both the Invasiveness and Proliferation of Cancer Cells and Underlying Cell Signals

The Cytoskeletal Protein Cyclase-Associated Protein 1 (CAP1) in Breast Cancer: Context-Dependent Roles in Both the Invasiveness and Proliferation of Cancer Cells and Underlying Cell Signals

As a conserved actin-regulating protein, CAP (adenylyl Cyclase-Associated Protein) functions to facilitate the rearrangement of the actin cytoskeleton. The ubiquitously expressed isoform CAP1 drives mammalian cell migration, and accordingly, most studies on the involvement of CAP1 in human cancers h...

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Bibliographic Details
Main Authors: Rokib Hasan, Guo-Lei Zhou
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer
CAP1
the actin cytoskeleton
cell adhesion
cell invasiveness
cell proliferation
ERK
FAK
Online Access:https://www.mdpi.com/1422-0067/20/11/2653

Internet

https://www.mdpi.com/1422-0067/20/11/2653

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