A microarray-based genetic screen for yeast chronological aging factors.

Model organisms have played an important role in the elucidation of multiple genes and cellular processes that regulate aging. In this study we utilized the budding yeast, Saccharomyces cerevisiae, in a large-scale screen for genes that function in the regulation of chronological lifespan, which is...

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Bibliographic Details
Main Authors: Mirela Matecic, Daniel L Smith, Xuewen Pan, Nazif Maqani, Stefan Bekiranov, Jef D Boeke, Jeffrey S Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2858703?pdf=render