Comparison of Mechanisms of Endothelial Cell Protections Between High-Density Lipoprotein and Apolipoprotein A-I Mimetic Peptide

Comparison of Mechanisms of Endothelial Cell Protections Between High-Density Lipoprotein and Apolipoprotein A-I Mimetic Peptide

Apolipoprotein A-I (apoA-I) mimetic peptide, D-4F, exhibits anti-atherogenic effects similar to high-density lipoprotein (HDL). However, it remains elusive whether D-4F and HDL share similar molecular mechanisms underlying anti-atherogenic effects and endothelial cell protections. We here compared t...

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Bibliographic Details
Main Authors: Wenqi Xu, Mingming Qian, Caihua Huang, Pengfei Cui, Wei Li, Qian Du, Shenghui Yi, Xiaohe Shi, Yansong Guo, Jianlan Zheng, Donghui Liu, Donghai Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pharmacology
Subjects:
high-density lipoprotein
apoA-I mimetic peptide
oxidized low-density lipoprotein
endothelial cell
metabolomics
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00817/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00817/full

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