Synthesis, cytotoxic and anti-proliferative activity of novel thiophene, thieno[2,3-b]pyridine and pyran derivatives derived from 4,5,6,7-tetrahydrobenzo[b]thiophene derivative
Novel tetrahydrobenzo[b]thienopyrole derivatives were synthesized from 2-amino-3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophene (1) through its reaction with α-chloroacetone to give the corresponding N-alkyl derivative 3. The latter underwent ready cyclization in sodium ethoxide solution to give the tetr...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Slovenian Chemical Society
2017-02-01
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| Series: | Acta Chimica Slovenica |
| Subjects: | |
| Online Access: | https://journals.matheo.si/index.php/ACSi/article/view/2920 |