Depletion of histone methyltransferase KMT9 inhibits lung cancer cell proliferation by inducing non-apoptotic cell death

Depletion of histone methyltransferase KMT9 inhibits lung cancer cell proliferation by inducing non-apoptotic cell death

Abstract Background Lung cancer is the leading cause of cancer related death worldwide. Over the past 15 years no major improvement of survival rates could be accomplished. The recently discovered histone methyltransferase KMT9 that acts as epigenetic regulator of prostate tumor growth has now raise...

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Bibliographic Details
Main Authors: Hannah Maria Baumert, Eric Metzger, Matthias Fahrner, Julie George, Roman K. Thomas, Oliver Schilling, Roland Schüle
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Cancer Cell International
Subjects:
Lung cancer
Non-small cell lung cancer
A549
Epigenetics
Histone methyltransferase
KMT9
Online Access:http://link.springer.com/article/10.1186/s12935-020-1141-2

Internet

http://link.springer.com/article/10.1186/s12935-020-1141-2

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