Melatonin Modulates the Microenvironment of Glioblastoma Multiforme by Targeting Sirtuin 1

Natural products have historically been regarded as an important resource of therapeutic agents. Resveratrol and melatonin have been shown to increase SIRT1 activity and stimulate deacetylation. Glioblastoma multiforme (GBM) is the deadliest of malignant types of tumor in the central nervous system...

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Bibliographic Details
Main Authors: Sheng-Wei Lai, Yu-Shu Liu, Dah-Yuu Lu, Cheng-Fang Tsai
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/11/6/1343