The degree of astrocyte activation is predictive of the incubation time to prion disease
Abstract In neurodegenerative diseases including Alzheimer’s, Parkinson’s and prion diseases, astrocytes acquire disease-associated reactive phenotypes. With growing appreciation of their role in chronic neurodegeneration, the questions whether astrocytes lose their ability to perform homeostatic fu...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-05-01
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Series: | Acta Neuropathologica Communications |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40478-021-01192-9 |