Increased circulating resistin levels in early-onset breast cancer patients of normal body mass index correlate with lymph node negative involvement and longer disease free survival: a multi-center POSH cohort serum proteomics study

Increased circulating resistin levels in early-onset breast cancer patients of normal body mass index correlate with lymph node negative involvement and longer disease free survival: a multi-center POSH cohort serum proteomics study

Abstract Background Early-onset breast cancer (EOBC) affects about one in 300 women aged 40 years or younger and is associated with worse outcomes than later onset breast cancer. This study explored novel serum proteins as surrogate markers of prognosis in patients with EOBC. Methods Serum samples f...

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Bibliographic Details
Main Authors: Bashar Zeidan, Antigoni Manousopoulou, Diana J. Garay-Baquero, Cory H. White, Samantha E. T. Larkin, Kathleen N. Potter, Theodoros I. Roumeliotis, Evangelia K. Papachristou, Ellen Copson, Ramsey I. Cutress, Stephen A. Beers, Diana Eccles, Paul A. Townsend, Spiros D. Garbis
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Breast Cancer Research
Subjects:
Quantitative serum proteomics
Resistin
Insulin resistance
Glycolysis/gluconeogenesis
lymph-node involvement
Early-onset breast cancer
Online Access:http://link.springer.com/article/10.1186/s13058-018-0938-6

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http://link.springer.com/article/10.1186/s13058-018-0938-6

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