Double-layered antibiotic-loaded cement spacer as a novel alternative for managing periprosthetic joint infection: an in vitro study

Abstract Background Previous studies comparing antibiotic-loaded calcium phosphate cement to polymethylmethacrylate cement reported that although the former has higher elution volumes over a longer period, it is mechanically weak when used alone. To counter this problem, a double-layered antibiotic-...

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Bibliographic Details
Main Authors: Shinsuke Ikeda, Katsufumi Uchiyama, Yojiro Minegishi, Keiko Ohno, Masaki Nakamura, Kazuhiro Yoshida, Kensuke Fukushima, Naonobu Takahira, Masashi Takaso
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13018-018-1033-5