Methylated genomic loci encoding microRNA as a biomarker panel in tissue and saliva for head and neck squamous cell carcinoma

Methylated genomic loci encoding microRNA as a biomarker panel in tissue and saliva for head and neck squamous cell carcinoma

Abstract Background To identify aberrant promoter methylation of genomic loci encoding microRNA (mgmiR) in head and neck squamous cell carcinoma (HNSCC) and to evaluate a biomarker panel of mgmiRs to improve the diagnostic accuracy of HNSCC in tissues and saliva. Methods Methylation of promoter regi...

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Bibliographic Details
Main Authors: Yu Cao, Katherine Green, Steve Quattlebaum, Ben Milam, Ling Lu, Dexiang Gao, Hui He, Ningning Li, Liwei Gao, Francis Hall, Matthew Whinery, Elyse Handley, Yi Ma, Tao Xu, Feng Jin, Jing Xiao, Minjie Wei, Derek Smith, Sophia Bornstein, Neil Gross, Dohun Pyeon, John Song, Shi-Long Lu
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Clinical Epigenetics
Subjects:
Head and neck squamous cell carcinoma
microRNA
DNA methylation
Biomarker
Tissue
Saliva
Online Access:http://link.springer.com/article/10.1186/s13148-018-0470-7

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http://link.springer.com/article/10.1186/s13148-018-0470-7

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