Creatine, Glutamine plus Glutamate, and Macromolecules Are Decreased in the Central White Matter of Premature Neonates around Term.

Preterm birth represents a high risk of neurodevelopmental disabilities when associated with white-matter damage. Recent studies have reported cognitive deficits in children born preterm without brain injury on MRI at term-equivalent age. Understanding the microstructural and metabolic underpinnings...

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Bibliographic Details
Main Authors: Meriam Koob, Angèle Viola, Yann Le Fur, Patrick Viout, Hélène Ratiney, Sylviane Confort-Gouny, Patrick J Cozzone, Nadine Girard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4993494?pdf=render